Exploring case–control genetic association tests using phase diagrams

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Exploring case-control genetic association tests using phase diagrams

BACKGROUND By a new concept called "phase diagram", we compare two commonly used genotype-based tests for case-control genetic analysis, one is a Cochran-Armitage trend test (CAT test at x=0.5, or CAT0.5) and another (called MAX2) is the maximization of two Chi-square test results: one from the two-by-two genotype count table that combines the baseline homozygotes and heterozygotes, and another...

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ژورنال

عنوان ژورنال: Computational Biology and Chemistry

سال: 2008

ISSN: 1476-9271

DOI: 10.1016/j.compbiolchem.2008.07.025